Research

EXTOD publications

Below are a list of the publication that have come from EXTOD studies or studies in which EXTOD has collaborated with other people.

Type 1 diabetes related

Effectiveness of Educational and Psychoeducational Self-Management Interventions in Children and Adolescents With Type 1 Diabetes: A Systematic Review and Meta-Analysis.Cockcroft EJ, Clarke R, Dias RP, Lloyd J, Mann RH, Narendran P, Reburn C, Smith B, Smith JR, Andrews RC. Pediatr Diabetes. 2024 Oct 8;2024:2921845. Link to paper

A mixed methods exploration of the experiences of physical activity providers in supporting children and adolescents with type 1 diabetes in the UK.Ngamy T, Statham L, Smith B, Smith JR, Lloyd J, Clarke R, Narendran P, Dias RP, Andrews RC, Cockcroft EJ.Eur J Pediatr. 2025 Apr 24;184(5):311. Link to paper

Can 4 weeks of real-world active breaks improve glycaemic management in sedentary adults with type 1 diabetes? The EXTOD-Active randomised control trial protocol.Jenkins JG, Cocks M, Narendran P, Andrews RC, Shields BM, Scott SN, Lucas SJE, Rendeiro C, Hesketh K.BMJ Open Sport Exerc Med. 2025 Apr 5;11(2):e002594. Link to paper

Impact of Recording Interval in Continuous Glucose Monitoring on Calculating the Metrics of Glycemic Control.Russon CL, Pulsford RM, Allen MJ, Cockcroft E, Vaughan N, Andrews RC.J Diabetes Sci Technol. 2025 Mar;19(2):590-592. Doi:10.1177/19322968241310892. Epub 2025 Jan 16. Link to paper

A User-Friendly Web Tool for Custom Analysis of Continuous Glucose Monitoring Data.Russon CL, Allen MJ, Pulsford RM, Saunby M, Vaughan N, Cocks M, Hesketh KL, Low J, Andrews RC.J Diabetes Sci Technol. 2024 Nov;18(6):1511-1513. doi: 10.1177/19322968241274322. Epub 2024 Sep 17. Link to paper

EXTOD-Immune: a randomised controlled trial to investigate whether a remotely monitored, home-based exercise intervention can reduce disease activity in people with type 1 diabetes.Quickfall M, Cocks M, Long HM, Di Rosa F, Andrews R, Narendran P, Hesketh K, Wadley AJ.BMJ Open Sport Exerc Med. 2024 Aug 30;10(3):e002144. Link to the paper

Recommendations from Diabetes UK's 2022 diabetes and physical activity workshop. Morris A, Bright C, Cocks M, Gibson N, Goff L, Greaves C, Griffin S, Jane B, Kinnafick F, Robb P, Roberts M, Salman D, Saxton J, Taylor A, West D, Yates T, Andrews RC, Gill JMR. Diabet Med. 2023 Sep;40(9):e15169. Link to paper

Factors affecting the support for physical activity in children and adolescents with type 1 diabetes mellitus: a national survey of health care professionals' perceptions. Cockcroft EJ, Wooding EL, Narendran P, Dias RP, Barker AR, Moudiotis C, Clarke R, Andrews RC.BMC Pediatr. 2023 Mar 22;23(1):131. Link to paper

The benefits of physical exercise for the health of the pancreatic β-cell: a review of the evidence.Curran M, Drayson MT, Andrews RC, Zoppi C, Barlow JP, Solomon TPJ, Narendran P.Exp Physiol. 2020 Apr;105(4):579-589. Link to paper

Exercise-induced hypoglycaemia in type 1 diabetes.Cockcroft EJ, Narendran P, Andrews RC.Exp Physiol. 2020 Apr;105(4):590-599. Link to the paper

Development of a group structured education programme to support safe exercise in people with Type 1 diabetes: the EXTOD education programme.Narendran P, Greenfield S, Troughton J, Doherty Y, Quann N, Thompson C, Litchfield I, Andrews RC; EXTOD Education Programme Development Team.Diabet Med. 2020 Jun;37(6):945-952. doi: 10.1111/dme.14064. Epub 2019 Jul 31. Link to paper

Multidisciplinary Evaluation of a Virtually Supervised Home-Based High-Intensity Interval Training Intervention in People With Type 1 Diabetes.Scott SN, Shepherd SO, Andrews RC, Narendran P, Purewal TS, Kinnafick F, Cuthbertson DJ, Atkinson-Goulding S, Noon T, Wagenmakers AJM, Cocks M. Diabetes Care. 2019 Sep 17. pii: dc190871. Link to paper

Development of a group structured education programme to support safe exercise in people with Type 1 diabetes: the EXTOD education programme. Narendran P, Greenfield S, Troughton J, Doherty Y, Quann N, Thompson C, Litchfield I, Andrews RC; EXTOD Education Programme Development Team. Diabet Med. 2019 Jul 2. Link to paper.

Patient and Healthcare Professionals Perspectives on the Delivery of Exercise Education for Patients With Type 1 Diabetes.. Litchfield I, Andrews RC, Narendran P, Greenfield S. Front Endocrinol (Lausanne). 2019 Feb 19;10:76. Link to paper.

Type 1 diabetes impairs the mobilisation of highly-differentiated CD8+T cells during a single bout of acute exercise. Curran M, Campbell J, Drayson M, Andrews R, Narendran P. Exerc Immunol Rev. 2019;25:64-82. Link to paper.

Objective Measurement of Physical Activity in Adults With Newly Diagnosed Type 1 Diabetes and Healthy Individuals. Matson RIB, Leary SD, Cooper AR, Thompson C, Narendran P, Andrews RC. Front Public Health. 2018 Dec 7;6:360. Link to paper.

High-Intensity Interval Training Improves Aerobic Capacity Without a Detrimental Decline in Blood Glucose in People With Type 1 Diabetes. Scott SN, Cocks M, Andrews RC, Narendran P, Purewal TS, Cuthbertson DJ, Wagenmakers AJM, Shepherd SO. J Clin Endocrinol Metab. 2019 Feb 1;104(2):604-612. Link to paper.

Fasted High-Intensity Interval and Moderate-Intensity Exercise Do Not Lead to Detrimental 24-Hour Blood Glucose Profiles. Scott SN, Cocks M, Andrews RC, Narendran P, Purewal TS, Cuthbertson DJ, Wagenmakers AJM, Shepherd SO. J Clin Endocrinol Metab. 2019 Jan 1;104(1):111-117. Link to paper

The Type 1 diabetes 'honeymoon' period is five times longer in men who exercise: a case-control study. Chetan MR, Charlton MH, Thompson C, Dias RP, Andrews RC, Narendran P. Diabet Med. 2019 Jan;36(1):127-128. Link to paper.

Qualitative study of barriers to clinical trial retention in adults with recently diagnosed type 1 diabetes. Henshall C, Narendran P, Andrews RC, Daley A, Stokes KA, Kennedy A, Greenfield S. BMJ Open. 2018 Jul 17;8(7):e022353. Link to paper.

Attitudes and barriers to exercise in adults with a recent diagnosis of type 1 diabetes: a qualitative study of participants in the Exercise for Type 1 Diabetes (EXTOD) study. Kennedy A, Narendran P, Andrews RC, Daley A, Greenfield SM; EXTOD Group. BMJ Open. 2018 Jan 24;8(1):e017813. Link to paper.

Exercise to preserve β-cell function in recent-onset Type 1 diabetes mellitus (EXTOD) - a randomized controlled pilot trial. Narendran P, Jackson N, Daley A, Thompson D, Stokes K, Greenfield S, Charlton M, Curran M, Solomon TPJ, Nouwen A, Lee SI, Cooper AR, Mostazir M, Taylor RS, Kennedy A, Andrews RC. Diabet Med. 2017 Nov;34(11):1521-1531. Link to paper.

The time has come to test the beta cell preserving effects of exercise in patients with new onset type 1 diabetes. Narendran P, Solomon TP, Kennedy A, Chimen M, Andrews RC.Diabetologia. 2015 Jan;58(1):10-8. Link to paper.

Attitudes and barriers to exercise in adults with type 1 diabetes (T1DM) and how best to address them: a qualitative study. Lascar N, Kennedy A, Hancock B, Jenkins D, Andrews RC, Greenfield S, Narendran P. PLoS One. 2014 Sep 19;9(9):e108019. Link to paper.

Type 2 diabetes related

Improved glycemic regulation on exercise compared to non-exercise days in a real-world setting in individuals recently diagnosed with type 2 diabetes: A secondary analysis of the MOTIVATE T2D randomised controlled trial.Low JL, Hesketh K, Falkenhain K, Jung ME, Singer J, Jones CA, Russon C, Andrews R, Cocks M, McManus AM, Little JP; MOTIVATE T2D Team.Diabetes Obes Metab. 2025 Jul 21. Link to paper

Mobile Health Biometrics to Enhance Exercise and Physical Activity Adherence in Type 2 Diabetes (MOTIVATE-T2D): a decentralised feasibility randomised controlled trial delivered across the UK and Canada.Hesketh K, Low J, Andrews R, Blitz S, Buckley B, Falkenhain K, Job J, Jones CA, Jones H, Jung ME, Little J, Mateus C, Percival SL, Pulsford R, Russon CL, Singer J, Sprung VS, McManus AM, Cocks M. BMJ Open. 2025 Mar 26;15(3):e092260. Link to paper

The impact of prolonged walking on fasting plasma glucose in type 2 diabetes: A randomised controlled crossover study. Niwaha AJ, Shields BM, Rodgers LR, Hattersley AT, Andrews RC, Nyirenda MJ, Jones AG.Diabet Med. 2025 Mar;42(3):e15468. Link to paper

Clinical Considerations and Practical Advice for People Living With Type 2 Diabetes Who Undertake Regular Exercise or Aim to Exercise Competitively. Scott SN, Hayes C, Zeuger T, Davies AP, Andrews RC, Cocks M.Diabetes Spectr. 2023 May;36(2):114-126. Link to paper

Electrically assisted cycling for individuals with type 2 diabetes mellitus: a pilot randomized controlled trial.Bourne JE, Leary S, Page A, Searle A, England C, Thompson D, Andrews RC, Foster C, Cooper AR. Pilot Feasibility Stud. 2023 Apr 18;9(1):60. Link to paper

Mobile Health Biometrics to Enhance Exercise and Physical Activity Adherence in Type 2 Diabetes (MOTIVATE-T2D): protocol for a feasibility randomised controlled trial.Hesketh K, Low J, Andrews R, Jones CA, Jones H, Jung ME, Little J, Mateus C, Pulsford R, Singer J, Sprung VS, McManus AM, Cocks M. BMJ Open. 2021 Nov 26;11(11):e052563. Link to paper

Benefits outweigh the risks: a consensus statement on the risks of physical activity for people living with long-term conditions.Reid H, Ridout AJ, Tomaz SA, Kelly P, Jones N; Physical Activity Risk Consensus group. Br J Sports Med. 2022 Apr;56(8):427-438. Link to paper

James Lind Alliance research priorities: should diet and exercise be used as an alternative to drugs for the management of type 2 diabetes or alongside them? England CY, Andrews RC. Diabet Med. 2020 Apr;37(4):564-572. Link to paper

Electrically assisted cycling for individuals with type 2 diabetes mellitus: protocol for a pilot randomized controlled trial. Bourne JE, Page A, Leary S, Andrews RC, England C, Cooper AR.Pilot Feasibility Stud. 2019 Nov 23;5:136. Link to paper

"I've made this my lifestyle now": a prospective qualitative study of motivation for lifestyle change among people with newly diagnosed type two diabetes mellitus.Sebire SJ, Toumpakari Z, Turner KM, Cooper AR, Page AS, Malpass A, Andrews RC.BMC Public Health. 2018 Jan 31;18(1):204. Link to paper

The Acute Effects of Breaking Up Seated Office Work With Standing or Light-Intensity Walking on Interstitial Glucose Concentration: A Randomized Crossover Trial. Brocklebank LA, Andrews RC, Page A, Falconer CL, Leary S, Cooper A.J Phys Act Health. 2017 Aug;14(8):617-625. doi: 10.1123/jpah.2016-0366. Epub 2017 Apr 19. Link to paper

The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes. Falconer CL, Page AS, Andrews RC, Cooper AR.Med Sci Sports Exerc. 2015 Oct;47(10):2070-5. Link to paper

Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes.Falconer CL, Cooper AR, Walhin JP, Thompson D, Page AS, Peters TJ, Montgomery AA, Sharp DJ, Dayan CM, Andrews RC.Nutr Metab Cardiovasc Dis. 2014 Sep;24(9):956-62. Link to paper

Effect of diet or diet plus physical activity versus usual care on inflammatory markers in patients with newly diagnosed type 2 diabetes: the Early ACTivity in Diabetes (ACTID) randomized, controlled trial.Thompson D, Walhin JP, Batterham AM, Stokes KA, Cooper AR, Andrews RC.J Am Heart Assoc. 2014 May 8;3(3):e000828. Link to paper

Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes.Cooper AR, Sebire S, Montgomery AA, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Dayan CM, Andrews RC. Diabetologia. 2012 Mar;55(3):589-99. Link to paper

Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial.Andrews RC, Cooper AR, Montgomery AA, Norcross AJ, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Bright J, Coulman K, England CY, Gorton J, McLenaghan A, Paxton E, Polet A, Thompson C, Dayan CM.Lancet. 2011 Jul 9;378(9786):129-39. Link to paper

Patients with Type 2 Diabetes experiences of making multiple lifestyle changes: a qualitative study.Malpass A, Andrews R, Turner KM.Patient Educ Couns. 2009 Feb;74(2):258-63. Link to paper